ıntra articular solutıons

alsavın

High Molecular Intraarticular Gels

Effective solution in arthrosis treatment

Longest and Monotype HA Chains with RDNA Biofermentation Technology

ALSAVINs contain 3 Million Dalton Longest and Monotype Sodium Hyaluronate produced by RDNA biofermantation technology.This High-tech Biotechnology procedure provides Pure & monotype material.

 

3 M DALTONS

RDNA BIOFERMENTATION

Recombinant microorganisms produce high-MW hyaluronic acid in monotype by expressing human genes

 

1-2.9 M DALTONS

OTHER FERMENTATION METHODS

Non-homogeneous mostly low MW HA chains are extracted from bacterial plasma and the cell wall

Suspensive HA structure

Well entangled ALSAVINs exhibit suspensive properties and the distance between HA chains supports stress absorption at molecular level.

Adaptive Elasticity

Elasticity of Intraarticular HA products plays a significant role in pain relief. The Adaptive Elasticity of Alsavins is increased by the stress frequency which provides progressive shock absorbtion while presenting highly elastic and suspensive responses.

Viscoisty(E’)-Elasticity(E”) of Alsavin and Healthy Synovial Fluid

10 mg/ml (1.0%): 20 mg HA in 2 ml solution

3-5 injections with one week intervals

RDNA Biofermentation

HA Structure: Suspensive

3.0 MDa molecular weight

Dynamic Viscosity: 60.000 mPa.s (Stable) 45.000 mPa.s (2,5 Hz)

Adaptive Elasticity: 200.000 mPa (2,5 Hz)

16 mg/ml (1.6%): 32 mg HA in 2 ml solution

1-3 injections with one week intervals

RDNA Biofermentation

HA Structure: Suspensive

3.0 MDa molecular weight

Dynamic Viscosity: 400.000 mPa.s (Stable) 80.000 mPa.s (2,5 Hz)

Adaptive Elasticity: 350.000 mPa (2,5 Hz)

20 mg/ml (2.0%): 48 mg HA in 2,4 ml solution

One Injection

RDNA Biofermentation

HA Structure: Suspensive

3.0 MDa molecular weight

Dynamic Viscosity: 900.000 mPa.s (Stable) 120.000 mPa.s (2,5 Hz)

Adaptive Elasticity: 600.000 mPa (2,5 Hz)